杨春娟，博士（后），教授，硕士生导师，药物分析与分析化学教研室副主任。2009年于沈阳药科大学获得药物分析博士学位。2009年7月入职哈尔滨医科大学药物分析与分析化学教研室，承担药物分析与分析化学教学工作。2012年哈尔滨医科大学博士后流动站出站。2013年以访问学者的身份在美国Rutgers大学澳门第一娱乐娱城官网进修。科研方向为中药材药效物质基础、质量标准及药物动力学研究；天然产物癌症预防及作用机制研究。主持国家自然科学基金3项, “地榆预防结肠癌的药效物质及其对Nrf2和NF-kB通路的表观遗传调控”(面上项目81573551)；“基于NF-kB和STAT3通路的表观遗传调控的平贝母多糖的分离纯化和肺癌预防” (面上项目81872979)； “苦地丁消除细菌耐药性的活性成分及作用机制”（ 青年基金81202875）；黑龙江省教育厅项目1项；黑龙江省自然科学基金项目1项；黑龙省卫生厅项目1项；哈尔滨市科技局创新项目1项。在国内外相关期刊杂志上发表科研论文30余篇，第一作者或通讯作者的SCI收录文章20余篇。2018年荣获哈尔滨医科大学师德师风优秀个人称号，2017年荣获哈尔滨医科大学优秀教师称号，2016年度澳门第一娱乐娱城官网优秀科技工作者称号，2013年度澳门第一娱乐娱城官网优秀青年教师及优秀青年工作者称号，2012年荣获哈尔滨医科大学青年教师讲课大赛一等奖，2012年度哈尔滨医科大学青年教师讲课大赛优秀奖。

发表文章情况：

1.Chunjuan Yang, Qi An, Zhili Xiong, Yang Song, Kai Yu, Famei Li. Triterpenes from Acanthopanax sessiliflorus fruits and their platelet anti-aggregating activities. Planta Medica, 2009, (75): 656-659.

2.Chunjuan Yang, Kai Yu, Yang Song, Feng Qin, Famei Li. Determination and pharmacokinetic study of chiisanogenin in rat plasma by ultra performance liquid chromatography-tandem mass spectrometry. Pharmachemical Analysis, 2010: DOI: 10.1002/pca.1269.

3.Chunjuan Yang, Zhibin Wang, Puyuan Song, Yang Xiao, Yonghai Meng, Yanyan Wang, Hai Jiang, Haixue Kuang. Monoterpenoids from Acanthopanax sessiliflorus Fruits. Molecules, 2013, 6(18): 3043-3049.

4.Chunjuan Yang, Xiao Y, Zhibin Wang, Shuhong Wang, Lijuan Chen, Lijun Wu, Gaofeng Liu. UHPLC-ESI-MS/MS determination and pharmacokinetic study of two alkaloid components in rat plasma after oral administration of the extract of Corydalis bungeana Turcz. J Chromatogr B, 2014, 960: 59-66.

5.Chunjuan Yang, Shuhong Wang, Xiaowei Guo, Jiahui Sun, Lu Liu, Lijun Wu. Simultaneous determination of seven anthraquinones in rat plasma By Ultra High PerformanceLiquid Chromatography–tandem Mass Spectrometry and pharmacokinetic study after oraladministrationof Semen Cassiae extract. Journal of Ethnopharmacology, 2015, 169: 305-313.

6.Lu Liu, Xueli Yu, Zhibin Wang, Jiahui Sun, Rong Pan, Chunjuan Yang, Lijun Wu. Simultaneous determination and pharmacokinetics of five alkaloids in rat plasma by ultra high performance liquid chromatography with tande mass spectrometry After the oral administration of Corydalis bungeana Turcz extract. J.Sep.Sci. 2016, 39(2), 296-305.

7.Chun-Juan Yang , Zhi-Bin Wang, Ying-Ying Mi, Ming-Jie Gao, Jin- Nan Ly, Yong-Hai Meng, Bing-You Yang and Hai-Xue Kuang . UHPLC-MS/MS Determination, Pharmacokinetic,and Bioavailability Study of Taxifolin in Rat Plasma after Oral Administration of its Nanodispersion. Molecules, 2016, 21(4), 494-505.

8.Mingjie Gao, Jing Yang, Zhibin Wang , Bingyou Yang, Haixue Kuang, LuLiu, Liqian Wang and Chunjuan Yang. Simultaneous Determination of Purpurin, Munjistin and Mollugin in Rat Plasma by Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry Application to a Pharmacokinetic Study after Oral Administration of Rubia cordifolia L. Extract. Molecules, 2016, 21(6), 717-730.

9.Lu Liu, Zhi-Bin Wang, Yang Song, Jing Yang, Li-Jun Wu, Bing-You Yang, Qiu-Hong Wang, Li-Qian Wang, Ru-Xuan Wang and Chun-Juan Yang. Simultaneous Determination of Eight Alkaloids in Rat Plasma by UHPLC-MS/MS after Oral Administration of Coptis deltoidea C. Y. Cheng et Hsiaoand Coptis chinensis Franch. Molecules, 2016, 21(7), 913-928.

10.Chunjuan Yang, Chengyue Zhang, Zhibin Wang, Zhenqiu Tang, Haixue Kuang and Ah-Ng Tony Kong. Corynoline Isolated from Corydalis bungeanaTurcz. Exhibits Anti-Inflammatory Effects via Modulation of Nfr2 and MAPKs. Molecules, 2016, 21(8), 975-990.

11.Chunli Gan, Lu Liu, Yan Du, Liqian Wang, Mingjie Gao, Lijun Wu, Chunjuan Yang.Simultaneous determination and pharmacokinetic study of four phenol compounds in rat plasma by ultra-high performance liquid chromatography with tandem mass spectrometry after oral administration of Echinacea purpurea extract. J.Sep.Sci. 2016, 39(9), 1628-1637.

12.Yan Du, Zhibin Wang, Libo Wang, Mingjie Gao, Liqian Wang, Chunli Gan, Chunjuan Yang*. Simultaneous Determination of Seven Phenolic Acids in Rat Plasma Using UHPLC-ESI-MS/MS after Oral Administration of Echinacea purpurea Extract.[J]. Molecules, 2017, 22(9):1494.

13.Mingjie Gao, Zhibin Wang, Jing Yang, Liqian Wang, Chengcui Wu, Binbin Cui, Chunjuan Yang*.Simultaneous determination and pharmacokinetics study of four quinones in rat plasma by ultra high performance liquid chromatography with electrospray ionization tandem mass spectrometry after the oral administration of Qianzhi capsules.[J]. Journal of Separation Science, 2018, 41(10):2105-2304.

14.Hongrui Dong，Guanyun Yan，Zhibin Wang, Chencui Wu, Binbin Cui, Yixuan Ren, Chunjuan Yang*. Liquid Chromatography-Tandem Mass Spectrometry Simultaneous Determination and Pharmacokinetic Study of Fourteen Alkaloid Components in Dog Plasma after Oral Administration of Corydalis bungeana Turcz Extract.[J] Molecules 2018, 23(8), 1927.

15.Binbin Cui, Jing Yang, Zhibin Wang, Chencui Wu, Hongrui Dong, Yixuan Ren, Chunjuan Yang*. An Ultra-High Performance Liquid Chromatography with Tandem Mass Spectrometry Method for Determination of 10 Alkaloids in Beagle Dog Plasma after the Oral Administration of the Corydalis yanhusuo W.T. Wang Extract and Yuanhuzhitong Tablets. [J] Molecules 2018, 23(8), 1925.

16Chengcui Wu, Meicun Yao, Wa Li, Binbin Cui, Hongrui Dong, Yixuan Ren, Chunjuan Yang, Chunli Gan.Simultaneous Determination and Pharmacokinetics Study of Six Triterpenes in Rat Plasma by UHPLC-MS/MS after Oral Administration of Sanguisorba officinalis L. Extract. [J] Molecules 2018, 23(8), 2980.

17Yixuan Ren, Zhibin Wang, Chengcui Wu, Hongrui Dong, Chunli Gan, Linzi Fan,Wenyu Wang, Chunjuan Yang. Ultrahigh-performance liquid chromatography with tandem massspectrometry for the determination of 10 alkaloids in beagle plasma after theoral administration of the three Coptidis rhizoma extracts.[J]. Journal of Ethnopharmacology, 2019, 239: 111896.

教材编写情况

1.2016.8 《质谱技术在临床医学中的应用》,人民卫生出版社，参编

2.2019.3，《药物分析》，化学工业出版社，参编

3.2019.7，《高等药物分析》，人民卫生出版社，参编